Still, the Swiss drugmaker kept that $85 per share as its “best and final offer.”, RELATED: Is $9.7B too big a price for The Medicines Company? As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. The Medicines Company will file today a Solicitation/Recommendation Statement on Schedule 14D-9 with the SEC, which includes, among other things, the recommendation of The Medicines Company board of directors that The Medicines Company’s stockholders accept the Offer and tender their shares of The Medicines Company common stock pursuant to the Offer. The Schedule TO Tender Offer Statement and related materials will be available for free under the “Investors – Financial Data – SEC Filings” section of Novartis’ website at https://www.novartis.com/investors/financial-data/sec-filings. The Offer will expire at 12:00 midnight, New York City time, at the end of the day on January 3, 2020, unless extended (the latest time and date at which the Offer will expire, the “Expiration Date”). Found inside – Page 316In May 2006, India's narrow approach to the patentability of medicines was challenged by pharmaceutical company Novartis, attracting outrage from proponents ... Since Narasimhan took over in February 2018, Novartis has announced almost $16 billion in acquisitions. Basel, December 5, 2019 — Novartis AG (NYSE: NVS) (“Novartis”) today announced that its indirect wholly-owned subsidiary, Medusa Merger Corporation, a Delaware corporation (“Purchaser”), has commenced a cash tender offer to purchase all of the outstanding shares of common stock, par value USD 0.001 per share, of The Medicines Company (NASDAQ: MDCO) for a price of USD 85.00 per share, net to the seller in cash, without interest and subject to any tax withholding (the “Offer”). After its $8.7 billion deal for gene therapy expert AveXis and a $2.1 billion bolt-on radiotherapy buyout of Endocyte in 2018, the Swiss pharma again made multibillion-dollar acquisitions this year. Shares of RNA interference biotech companies surged Monday after Novartis (NVS) announced its $9.7 billion takeover of The Medicines Company (MDCO), adding a promising cholesterol treatment to its wheelhouse.. X. Under the terms of the deal, Novartis is paying $85 per share in cash, which is about a 41% premium of The Medicines Company’s … Found inside – Page 232Novartis- — the parent company of Ciba — has taken a different approach. According to the Wall Street Journal, Novartis continued to use Borison and Diamond ... Found inside – Page 208numbers of people. it was very hard to interest companies in developing inhibitors ... Novartis had so little interest in committing resources to the drug's ... Swiss pharma giant Novartis NVS is the latest company to join the ongoing M&A wave in the pharma/biotech sector. There are several risks with the latest acquisition by Novartis.The first item of risk to note involves inclisiran itself. Novartis AG said Wednesday that its generics division Sandoz has entered into a commercialization agreement with biopharmaceutical company Bio-Thera Solutions, Ltd. for oncology medicine biosimilar bevacizumab. Yancy and Harrington discuss the new ACC/AHA cholesterol guidelines and CV risk calculator with committee vice chair Dr. Robinson. Yes, Novartis Chief Executive Officer Vas Narasimhan pulled the trigger on a deal to get one particular type of medicine … On December 5, 2019, Purchaser and Novartis will file a Tender Offer Statement on Schedule TO with the SEC and The Medicines Company will file a Solicitation/Recommendation Statement on Schedule 14D-9 with the SEC, in each case with respect to the Offer. Found inside36 the drug companies. ... The drug company Novartis (which produces Ritalin) and CHADD have together released material that promotes ADHD as a proven ... Novartis will file today a Tender Offer Statement on Schedule TO with the United States Securities and Exchange Commission (the “SEC”). Novartis will pay $85 per share for the New Jersey biotech company, a sharp increase over The Medicine Co.’s Friday closing price of $68.55 per share. The Zacks analyst believes that Novartis’ performance in the year so far has been stellar on key drugs like Cosentyx and Entresto, its contribution from Zolgensma, and the Xiidra acquisition. Over the last year, the companies have cut their drug prices to try to get more traction in the market. Novartis has agreed to acquire The Medicines Company for about $9.7bn to add inclisiran, an investigational cholesterol-lowering drug, to its cardiovascular portfolio. Novartis itself seems to think so. The Offer is being made upon the terms and subject to the conditions set forth in the Offer to Purchase, dated December 5, 2019, and the related Letter of Transmittal and pursuant to the terms of the previously announced Agreement and Plan of Merger, dated as of November 23, 2019 (the “Merger Agreement”), among Novartis, Purchaser and The Medicines Company. Actually make that medicine singular. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. The ORION-10 trial met all primary and secondary efficacy endpoints. Novartis/The Medicines Company Additional InformationThis press release is neither an offer to purchase nor a solicitation of an offer to sell securities. The safety signals for inclisiran was similar to the placebo group. Found insideHuman Rights, Intellectual Property Rules and Access to Medicines Dr Suerie ... the flexibilitiesin the country's newpatent lawwhen drug company Novartis ... Swiss pharmaceutical company Novartis has reached a deal to buy cholesterol drugmaker The Medicines Co. for $9.7 billion. Shares of The Medicines Company MDCO surged almost 20% on Nov 19 following a Bloomberg report about a potential acquisition of the company by Swiss pharma giant, Novartis NVS.. Just as Sanofi and Regeneron’s Praluent and Amgen’s Repatha do, inclisiran targets PCSK9 to reduce bad cholesterol levels. Found inside – Page 160Translational medicine includes any kind of diagnostic or therapeutic intervention, ... The drug company Novartis, as well as cancer funding agencies, ... Inclisiran can be dosed twice a year and the pricing is expected to be lower. Found inside – Page 390Glivec is an important drug for Novartis, grossing US$2.17 billion in global sales for the company in 2005.29 3.1 Patent claim by Novartis In 1998 Novartis ... Such forward-looking statements are based on our current beliefs and expectations regarding future events, and are subject to significant known and unknown risks and uncertainties. Found inside – Page 169Novartis , a Swiss drug company , agreed to cut the price of Riamet for sale to the World Health Organization . Priced at about $ 12 in industrialized ... Turns out, the Swiss drugmaker apparently thought so, too. Found inside... million through a shell company to provide access to Trump's administration and healthcare agenda, which the drug company Novartis never received and, ... The drug demonstrated placebo-adjusted LDL-C decreases of 58% at day 510, and showed time-averaged placebo-adjusted LDL-C decreases of 56% from day 90 through day 540. However, a large clinical trial evaluating whether inclisiran decreases heart attacks and stroke is still ongoing. Novartis has agreed a $9.7bn cash deal to acquire The Medicines Company, betting that the US drugmaker will come good on a new drug designed to control cholesterol levels. The Medicines Company is in late-stage studies of a drug, inclisiran, meant to lower cholesterol. The company focuses on researching treatments for cardiovascular disease, specifically looking at ways to lower so-called bad cholesterol. Novartis in recent years has used acquisitions to expand its portfolio of drugs. Found insideEmploying approximately 108,000 people across the globe, Novartis's treatments ... Novartis is a global medicines company based in Switzerland dedicated to ... Those drugs are dosed once every two weeks or monthly. While they’re in different cardiovascular indications, Entresto prescribers represent about 80% of prescribers of statins or existing PCSK9s in the U.S., Narasimhan noted. Amidst rumors that Novartis might be interested in an acquisition, The Medicines Company announced data from ORION-10, the second of three 19-month Phase III trials of inclisiran for lowering cholesterol. Any extension of the Offer will be followed by public announcement of the extension by press release or other public announcement before 9:00 a.m., New York City time, on the next business day after the Expiration Date. Found inside – Page 13... The Medicines Company, AstraZeneca, Janssen Pharmaceuticals, Osprey Medical Inc, Novartis, CSL Behring and Gilead. a Cardio-Thoracic-Vascular Department ... About NovartisNovartis is reimagining medicine to improve and extend people’s lives. A physician and former editor-in-chief of The New England Journal of Medicine provides an explosive critique of the pharmaceutical industry, detailing its dangerous influence on medical research, education, and physicians; exposing the ... Found inside – Page 49... 4.56 Product : pimecrolimus ( Elidel ) ; Drug company : Novartis Pimecrolimus cream for atopic dermatitis ( DTB article published May 2003 ) . Novartis agreed to buy The Medicines Company for $85 per share in a $9.7 billion cash transaction, a price that some say is too high. Found inside – Page 647... received speaker's honoraria from The Medicines Company, Novartis, Orion, ... Committee from Cardiorentis, The Medicine Company, Adrenomed, MyCartis, ... Its medicines, of course. The Company markets Angiomax(R) (bivalirudin) in the United States and other countries for use in patients undergoing coronary angioplasty, and Cleviprex(R) The difference is, the MedCo drug uses a small-interfering RNA technology developed by Alnylam Pharmaceuticals, while the two marketed drugs are antibodies. Despite previous excitement about PCSK9 inhibitors, Repatha and Praluent have not lived up to the Street’s original expectations. Novartis is to buy The Medicines Company and its cholesterol-lowering drug for $9.7 billion, confirming press speculation. © 2021 Questex LLC. Research Fabrikstrasse 2 Novartis Campus CH-4056 Basel “We are excited about entering into an agreement to acquire The Medicines Company as inclisiran is a potentially transformational medicine that reimagines the treatment of atherosclerotic heart disease and familial hypercholesterolemia,” said Vas Narasimhan, chief executive officer of Novartis. Found insideHow Companies Succeed by Engaging Radically with Society John Browne, Robin Nuttall, ... The drug company Novartis has reached an extra 42 million people by ... Basel, January 6, 2020 — Novartis AG (NYSE: NVS) (“Novartis”) today announced that it has completed the acquisition of The Medicines Company (the “Company”) through the consummation of a merger of its indirect wholly-owned subsidiary, Medusa Merger Corporation (“Purchaser”), with and into the Company, with the Company surviving the merger, without a vote of the Company’s … Nor can there be any guarantee that inclisiran will be submitted or approved for sale in any market, or at any particular time. Found inside – Page 247It focuses on the lawsuit brought by the drug company Novartis against the Indian government over the patent for the anti‐cancer drug Glivec. With the intention of revolutionising the treatment of cardiovascular disease around the world, biopharmaceutical firm The Medicines Company is to be acquired by Swiss multinational Novartis International AG – one of the world’s largest manufacturers of pharmaceuticals – in … The biotech company licensed inclisiran from Alnylam Pharmaceuticals (ALNY). The study was not powered to reach any conclusion on that score, but it did raise doubts about inclisiran's all-important cardiovascular outcomes trial Orion-4, which is expected to read out in 2023. All rights reserved. Another aspect of the drug that may draw skepticism from investors is that it’s a PCSK9 inhibitor. © 1985 - 2021 BioSpace.com. DisclaimerThis press release contains forward-looking statements within the meaning of the United States Private Securities Litigation Reform Act of 1995, that can generally be identified by words such as “tender offer,” “commences,” “commenced,” “to purchase,” “offer,” “will,” “subject to,” “conditions,” “unless extended,” or similar expressions, or by express or implied discussions regarding the potential outcome of the tender offer for The Medicines Company being commenced by Novartis. Found insideHow the Pharmaceutical Companies Transformed Themselves into Slick ... The drug company Novartis hired the Pepsi marketer Thomas Ebeling and by 2000 had ... This site is intended for a global audience. … Though it’s buying the entire firm, the deal is … Novartis' $9.7 billion price for The Medicines Company raised concerns that the Swiss drugmaker might have overpaid. exclude terms. However, inclisiran may have an advantage over Praluent and Repatha. In comparison, the current annualized sales for Repatha and Praluent combined are just $1 billion. In February 2019, Sanofi and Regeneron slashed Praluent’s price to $5,850 per year. The company has confirmed that the purchase was decided on the back of TMC’s recent data from its comprehensive clinical program, consisting of three inclisiran Phase III … Novartis to acquire The Medicines Company. He went on to say, “With tens of millions of patients at higher risk of cardiovascular events from high LDL-C, we believe that inclisiran could contribute significantly to improved patient outcomes and help healthcare systems address the leading global cause of death. Found inside – Page 128In 2019, Swiss drug company Novartis (U$ 194 billion market value as of May 2019) funded a large scale study proving that the MMR vaccine didn't cause ... Found inside... and other companies via his shell company until it was outed by the WSJ. ... which the drug company Novartis never received and, in turn, caught the eye ... The same day the data were revealed, Novartis withdrew its $90 offer and told MedCo that it wasn’t worth even $85, according to a Securities and Exchange Commission filing. The Offer to Purchase contained within the Schedule TO sets out the full terms and conditions of the Offer. Updated Nov 21, 2019 Biotech firm The Medicines Company (MDCO) rocketed to a fresh all-time high (ATH) Tuesday after Bloomberg reported that Novartis AG (NVS) was looking to acquire the company. Novartis is on Twitter. The impending acquisition of The Medicines Company should broaden its portfolio. Besides the convenience edge, MedCo CEO Mark Timney has also argued that the drug’s administration by a healthcare provider could help improve compliance. Found inside – Page 283Table A.2 (continued) Medicine Company SKU MRP Ceiling PTR Fluconazole Novartis India Ltd Flucess 150 mg tablet 1 32 14.45 4 Fluconazole Novartis India Ltd ... Found insideThrough a program called Compassionate Use, Bill Solomon has worked with the drug company Novartis to get Ms. Tulloch her medication for free. Found insideA week later, McNamara received a letter from the company's head of Clinical Research and Development, which read: “Novartis has devoted substantial ... Shares of The Medicines Company were up nearly 23% on Monday after Novartis said Sunday that it had agreed to buy the single-drug, clinical-stage biotech company for $85 per share. Those materials and all other documents filed by, or caused to be filed by, Novartis, Purchaser or The Medicines Company with the SEC will be available at no charge on the SEC’s website at www.sec.gov. Found inside – Page 312G.C.F.: research grant, NIH; consultant, Novartis. ... Abbott, Alere, Beckman Coulter, Electrocore, The Medicine's Company; speaker's bureau, Abbott, Alere; ... Amgen cut the price of Repatha in October 2018 to about $4,500 to $6,600 a year from an original price of about $14,000 for a year’s supply. Making Medicines Affordable examines patient access to affordable and effective therapies, with emphasis on drug pricing, inflation in the cost of drugs, and insurance design. The transaction was unanimously approved by the Boards of Directors of both companies. Novartis is providing the information in this press release as of this date and does not undertake any obligation to update any forward-looking statements as a result of new information, future events or otherwise. Novartis is a global healthcare company based in Switzerland that provides solutions to address the evolving needs of patients worldwide. Inclisiran is given twice a year after two initial lead-in injections, compared with every two weeks or once a month for the two PCSK9 antibodies. Found inside – Page 127In this instance, a socially responsible Swiss drug company, Novartis, ... recognizing the importance of access to the medicine, has provided it free or at ... Reproduction in whole or part is prohibited. The prospect of bringing inclisiran to patients also fits with our overall strategy to transform Novartis into a focused medicines company and adds an investigational therapy with the potential to be a significant driver of Novartis’ growth in the medium to long term.”. Found inside – Page 15921 “When the drug company Novartis launched its breakthrough cancer medicine, Gleevec, in 2001, the list price was $26,400 a year. Found inside – Page 205Nanomedicines based on emulsions on the market and under clinical ... a Novartis company Marketed Cleviprex® Clevidipine o/w emulsion High blood pressure ... Novartis has become quite acquisitive since Vas Narasimhan took over as CEO. About 109,000 people of more than 140 nationalities work at Novartis around the world. Novartis agreed to buy The Medicines Company for $85 per share in a $9.7 billion cash transaction, a price that some say is too high. The Medicines Company Pharmaceuticals East Hanover, NJ 11,140 followers With the acquisition of The Medicines Company by Novartis completed, this page is no longer active. Found inside – Page 78The papers were Slanted to make the drug companies' products look good, ... One example of ghostwriting occurred in 2002, when Novartis was trying to market ... It's official: After days of rumors, Novartis over the weekend said it had agreed to a $9.7 billion (€8.8 billion) deal to buy The Medicines Company in order to get its hands on next-gen heart drug inclisiran. It is the first and only in the small-interfering RNA (siRNA) class. There can be no guarantee that the proposed acquisition described in this press release will be completed, or that it will be completed as currently proposed, or at any particular time. When Novartis unveiled its $9.7 billion buyout of The Medicines Company a few days ago, several analysts suggested the price was too high. Nevertheless, on a conference call in November, Narasimhan said his company could make it work, what with its 50-years-plus experience in cardiovascular disease. The boards of both companies have unanimously approved the acquisition. Narasimhan is likely betting Novartis can make similar progress with inclisiran. Amidst Novartis Takeover Rumors, The Medicines Company Announces Positive Cholesterol Data. Found inside – Page 161... the competition of its generic version coming from the Indian drug company. Novartis regarded this settlement as a validation of the Gleevec patent. “We felt the commercial case—injectable drugs for a ‘silent’ disease, entering a highly-genericized category—would be challenging, and this is how it has played out,” Wolfe Research analyst Tim Anderson wrote in a recent note about the MedCo deal in the context of the slow launch of Repatha and Praluent. No, Hudson told him. Found insideIn 1994, the drug company Novartis attempted to make an end run around the DEA. CHADD, a parents' group that was at the time receiving large amounts of ... Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those set forth in the forward-looking statements. Found inside – Page 110The Novartis drug company sells Zelnorm, a laxative. Originally, its ads were aimed at women only; later it broadened its market to men as well. Though it’s buying the entire firm, the deal is really just about one drug: cardiovascular contender inclisiran. In our quest to find new medicines, we consistently rank among the world’s top companies investing in research and development. It is one of the largest pharmaceutical companies in the world. Novartis has announced plans to acquire The Medicines Company (TMC), in a deal worth $9.7 billion. This is because The Medicines Company acquired the drug from Alnylam and will have to split profit with them. ). Novartis's Sandoz Enters Commercialization Agreement for Oncology Medicine. Novartis International AG is a Swiss multinational pharmaceutical company based in Basel, Switzerland. Found inside – Page 351Today Jimenez is CEO of Novartis, one of the world's largest pharmaceutical companies. Novartis teamed with Americas's VetDogs to train and provide guide ... Subscribe to FiercePharma to get industry news and updates delivered to your inbox. Novartis also spun off the Alcon eye-care division and unloaded its stake in a consumer-health venture. Found inside – Page 388that would , for example , buy coal from mining companies at a fixed price ... The Swiss drug company , Novartis , objected to the sale of generics of its ... Medicines Co., the developer of a promising cholesterol drug, has attracted takeover interest from suitors including Novartis AG, people familiar with the matter said. Photo: courtesy of Novartis AG. The Offer is subject to customary closing conditions, including the tender of at least a majority of the outstanding shares of The Medicines Company common stock and the expiration or termination of the applicable waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976. Even ahead of the full data disclosure, SVB Leerink analyst Geoffrey Porges has predicted that inclisiran could make “the already challenging market for the antibodies unattractive.”. The Medicines Company (NASDAQ: MDCO) has entered into definitive agreement in which Novartis AG will acquire The Medicines Company for $85 per share in an all-cash transaction, implying a fully diluted equity value of $9.7 billion. Shares of The Medicines Company, a biotech firm developing a cholesterol-lowering treatment, soared Tuesday after a Bloomberg report said pharma giant Novartis was looking into a … The Medicines Company expects to use the data to submit for a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) before the end of the year and in Europe in the first quarter of 2020. The … The acquisition appears to assume inclisiran will create more than $2 billion in annual sales, according to Umer Raffat, an analyst at Evercore/ISI. You should not place undue reliance on these statements. At least three groups of analysts predicted Novartis will need to work hard to make the deal pay off—and still might not find its investment worthwhile. Published: Nov 25, 2019 Novartis Institutes for Biomed. Found inside – Page 109Novartis acquired the rights to market the therapy outside China, while Chinese companies continued to supply the raw material for the drug to Novartis. The Offer is subject to other important conditions set forth in the Offer to Purchase. The Offer is not subject to a financing condition. The Medicines Company plans to apply for FDA approval of inclisiran in the fourth quarter. SAN FRANCISCO—In a multibillion-dollar bet on the cholesterol drug candidate inclisiran, Novartis late last year picked up the Medicines Company in one of 2019's largest biopharma M&A deals. Novartis is reimagining medicine to improve and extend people’s lives. Medicines makes inclisiran, which treats elevated LDL cholesterol. Found inside... by the Swiss pharmaceutical company Novartis. The case concerned Glivec, an important and expensive drug in the treatment of myeloid leukaemia. By Mark Terry. The dosing interval “aligns with when these types of patients visit their physician, and therefore is starting to get these additive benefits such as the ability to control adherence,” he said. Enclose phrases in quotes. https://www.themedicinescompany.com/investor/financial/. Found insideThis company with unlimited potential is currently having to work hard just to keep up ... Novartis received marketing clearance from the U.S. Food and Drug ... Use a + to require a term in results and - to Found inside... with nearly $114,000 from drug companies for consulting and speaking. ... who did not disclose any relationship with the drug company Novartis when ... Is $9.7B too big a price for The Medicines Company? Innisfree M&A Incorporated is acting as information agent for Purchaser in the Offer. However, when it came to the Orion-10 data at the American Heart Association conference on Nov. 18, the drug, while posting a placebo-adjusted drop in LDL cholesterol of 58%, failed to deliver improvement on an exploratory endpoint that examined cardiovascular events. Requests for documents and questions by stockholders relating to the Offer may be directed to Innisfree M&A Incorporated by telephone at 1 (888) 750-5834 (toll free). Found insideAngiomax® is a registered trademark of The Medicine Company, Parsippany, NJ. Aredia® is a registered trademark of Novartis Pharmaceuticals Corporation, ... The Tender Offer Statement (including the Offer to Purchase, the related Letter of Transmittal and other offer documents) and the Solicitation/Recommendation Statement contain important information that should be read carefully when they become available and considered before any decision is made with respect to the Offer. Novartis itself seems to think so. By Evercore ISI analyst Umer Raffat’s calculation, the price Novartis is paying indicates $2.2 billion in inclisiran peak sales. American Stock Transfer & Trust Company, LLC is acting as the depositary and paying agent in the Offer. Found inside – Page 205Make Yourself and Your Company Resilient in the Age of Constant Change Baba ... of new medicines,” says a statement from the Swiss drug company Novartis. Novartis will pay $85 a … Novartis' $9.7 billion acquisition of The Medicines Company, which the companies announced Sunday after days of rumors, is a story of second … Find out more atwww.novartis.com. Novartis (NVS) to Acquire The Medicines Company for $9.7B. The focus appears to be on bolstering the company’s oncology and rare disease portfolio. Found inside – Page 21At that point in time, Ciba-Geigy and Sandoz merged to create the second largest drug company, Novartis. Novartis had little interest in developing drugs ... Found insideInApril 2013 the SupremeCourt of Indiaruled against the drug company Novartis on its claim for a patent on the lucrative andwidely used cancer drug ... Found insideAt present, only one drug company, Novartis of Switzerland, meets the standards. Its product, Coartem, is available in Nigerian pharmacies at more than $20 ... Found inside – Page 33Case study—Novartis iN iNdia In early 2003, Swiss drug company Novartis AG launched its anti-cancer drug Gleevec in the US market, after obtaining it's US ... Sign up to follow @Novartis at http://twitter.com/novartisnewsFor Novartis multimedia content, please visit www.novartis.com/news/media-libraryFor questions about the site or required registration, please contact [email protected], Novartis Media RelationsE-mail: [email protected], Eric AlthoffNovartis US Communications+1 646 438 4335 (mobile)[email protected], Novartis Investor RelationsCentral investor relations line: +41 61 324 7944E-mail: [email protected]. Industry news and updates delivered to your inbox the focus appears to be on bolstering the.... Uses a small-interfering RNA technology developed by Alnylam Pharmaceuticals ( ALNY ) 16 billion in acquisitions aimed at women ;. Approved by the Boards of Directors of both companies a validation of the world and conditions of the Company! Impending acquisition of the Gleevec patent and Amgen ’ s price to $ 5,850 per year –. $ 90 per share for the Company ’ s lives Umer Raffat ’ s price to $ 5,850 per.. Novartis in recent years has used acquisitions to expand access to our treatments! Bolstering the Company focuses on researching treatments for cardiovascular disease, specifically looking ways... An investigational twice-yearly drug to reduce low-density lipoprotein cholesterol ( LDL-C ) placebo.. Umer Raffat ’ s buying the entire firm, the MedCo drug uses a small-interfering RNA ( siRNA ).... 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